16.3 ABSORPTION OF DIGESTED PRODUCTS
16.3 ABSORPTION OF DIGESTED PRODUCTS
- Absorption is the process by which the end products of digestion pass through the intestinal mucosa into the blood or lymph.
- It is carried out by passive, active or facilitated transport mechanisms.
- Small amounts of monosaccharides like glucose, amino acids and some electrolytes like chloride ions are generally absorbed by simple diffusion.
- The passage of these substances into the blood depends upon the concentration gradients.
- However, some substances like glucose and amino acids are absorbed with the help of carrier proteins. This mechanism is called the facilitated transport.
- Transport of water depends upon the osmotic gradient.
- Active transport occurs against the concentration gradient and hence requires energy.
- Various nutrients like amino acids, monosaccharides like glucose, electrolytes like Na+ are absorbed into the blood by Active transport mechanism.
- Fatty acids and glycerol being insoluble, cannot be absorbed into the blood.
- They are first incorporated into small droplets called micelles which move into the intestinal mucosa.
- They are re-formed into very small protein coated fat globules called the chylomicrons which are transported into the lymph vessels (lacteals) in the villi.
- These lymph vessels ultimately release the absorbed substances into the blood stream.
Molecules
|
Mode of transport
|
Glucose, amino-acids and some electrolytes
like chloride ions (Cl-)
|
Absorbed by simple diffusion
|
Glucose (Glut-1 to 4), fructose (Glut-5) and
amino acids
|
Facilitated transport (carrier proteins)
|
Glucose, electrolytes like Na+
|
Active transport
|
Water
|
Osmotic gradient
|
Fatty acids and Glycerol
|
Micelles> Chylomicrons> Lymph vessels (lacteals)
|
- Absorption of substances takes place in different parts of the alimentary canal, like mouth, stomach, small intestine and large intestine.
- However, maximum absorption occurs in the small intestine.
- A summary of absorption (sites of absorption and substances absorbed) is given in Table 16.1.
- Assimilation: The absorbed substances finally reach the tissues which utilise them for their activities, this process is called assimilation.
- The digestive wastes, solidified into coherent faeces in the rectum initiate a neural reflex causing an urge or desire for its removal.
- The egestion of faeces to the outside through the anal opening (defaecation) is a voluntary process and is carried out by a mass peristaltic movement.
16.4 DISORDERS OF DIGESTIVE SYSTEM
- The inflammation of the intestinal tract is the most common ailment due to bacterial or viral infections.
- The infections are also caused by the parasites of the intestine like tapeworm, roundworm, threadworm, hookworm, pin worm, etc.
- Jaundice: The liver is affected, skin and eyes turn yellow due to the deposit of bile pigments.
- Vomiting: It is the ejection of stomach contents through the mouth. This reflex action is controlled by the vomit centre in the medulla. A feeling of nausea precedes vomiting.
- Diarrhoea: The abnormal frequency of bowel movement and increased liquidity of the faecal discharge is known as diarrhoea. It reduces the absorption of food.
- Constipation: In constipation, the faeces are retained within the rectum as the bowel movements occur irregularly.
- Indigestion: In this condition, the food is not properly digested leading to a feeling of fullness. The causes of indigestion are inadequate enzyme secretion, anxiety, food poisoning, over eating, and spicy food.
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